A 43-year-old female presented with blood loss and persistent abdominal pain at 14 weeks of gestation. Ultrasound examination and subsequent magnetic resonance imaging (MRI) revealed bilateral multicystic uterine adnexa. Exploratory laparotomy was performed at 17 weeks of gestation and bilateral serous ovarian adenocarcinoma FIGO stage IIIC was diagnosed. Complete cytoreductive surgery (CRS) was not feasible at that moment. Nine days after the exploratory laparotomy, immature rupture of membranes and contractions occurred and she delivered a premature boy after 19 weeks of gestation. Pathological examination of the placenta revealed that her ovarian cancer metastasized to the membranes. We describe the first case of ovarian cancer metastasized to the decidua of the placental membranes with histological, immunohistochemical, and molecular confirmation. This case highlights the importance of conscientious evaluation of placenta and membranes in pregnant women with ovarian cancer.

中文翻译：

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首次报道组织学和分子证实的双侧高级别浆液性卵巢腺癌转移至胎盘蜕膜

一名 43 岁女性在妊娠 14 周时出现失血和持续腹痛。超声检查和随后的磁共振成像（MRI）显示双侧多囊性子宫附件。妊娠17周时进行剖腹探查，诊断为双侧浆液性卵巢腺癌FIGO IIIC期。完全细胞减灭术（CRS）在当时是不可行的。剖腹探查术后九天，发生未成熟胎膜破裂和宫缩，妊娠 19 周后产下一名早产男婴。胎盘病理检查显示，她的卵巢癌已转移至胎膜。我们描述了第一例卵巢癌转移至胎盘膜蜕膜的病例，并通过组织学、免疫组织化学和分子证实。该病例强调了认真评估患有卵巢癌的孕妇的胎盘和胎膜的重要性。