The albumin-bilirubin (ALBI) score is considered an effective and convenient scoring system for assessing liver function. We hypothesized that the ALBI score was predictive of contrast-associated acute kidney injury (CA-AKI) and long-term mortality in patients undergoing elective percutaneous coronary intervention (PCI). We retrospectively observed 5629 patients undergoing elective PCI. Contrast-associated acute kidney injury is defined as a 50% or 0.3 mg/dl increase in baseline serum creatinine levels within 48 h of contrast exposure. The incidence of CA-AKI was 6.2% (n = 350). After adjusting for potential confounding factors, multivariate analysis showed that the ALBI score was an independent predictor of CA-AKI ( P = .002). A restricted cubic spline analysis confirmed approximately linear relationships between the ALBI score and risks of CA-AKI. Furthermore, at a median follow-up of 2.8 years, multivariate Cox regression analysis indicated that the ALBI score was an independent risk factor for long-term mortality ( P < .001). The ALBI score was closely related to the occurrence of CA-AKI and long-term mortality in patients who underwent elective PCI. This score might be useful for risk stratification in high-risk patient groups to predict CA-AKI.

中文翻译：

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择期经皮冠状动脉介入治疗患者白蛋白-胆红素评分与造影剂相关急性肾损伤之间的关联

白蛋白-胆红素（ALBI）评分被认为是评估肝功能的有效且方便的评分系统。我们假设 ALBI 评分可以预测接受择期经皮冠状动脉介入治疗 (PCI) 的患者的对比剂相关急性肾损伤 (CA-AKI) 和长期死亡率。我们回顾性观察了 5629 名接受择期 PCI 的患者。对比剂相关急性肾损伤定义为对比剂暴露 48 小时内基线血清肌酐水平增加 50% 或 0.3 mg/dl。CA-AKI 的发生率为 6.2% (n = 350)。调整潜在的混杂因素后，多变量分析表明 ALBI 评分是 CA-AKI 的独立预测因子 ( P = .002)。受限三次样条分析证实了 ALBI 评分与 CA-AKI 风险之间的近似线性关系。此外，在中位随访 2.8 年时，多变量 Cox 回归分析表明 ALBI 评分是长期死亡率的独立危险因素 ( P < .001)。ALBI评分与择期PCI患者CA-AKI的发生及长期死亡率密切相关。该评分可能有助于对高危患者组进行风险分层以预测 CA-AKI。