Introduction:Preserving the endocrine and reproductive function in young female cancer patients undergoing pelvic radiation is a significant challenge. While the photon beam radiation's adverse effects on the uterus and ovaries are well established, the impact of pelvic carbon ion radiotherapy on women's reproductive function is largely unexplored. Strategies such as oocyte cryopreservation and ovarian transposition are commonly recommended for safeguarding future fertility.Methods:This study presents a pioneering case of successful pregnancy after carbon ion radiotherapy for locally advanced sacral chondrosarcoma.Results:A multidisciplinary approach facilitated the displacement of ovaries and uterus before carbon ion radiotherapy, resulting in the preservation of endocrine and reproductive function.Conclusion:The patient achieved optimal oncological response and delivered a healthy infant following the completion of cancer treatment.

中文翻译：

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盆腔碳离子放射治疗后还可以生育吗？一种有前途的生育力保存联合方法

简介：保留接受盆腔放射的年轻女性癌症患者的内分泌和生殖功能是一项重大挑战。虽然光子束辐射对子宫和卵巢的不利影响已得到充分证实，但盆腔碳离子放射治疗对女性生殖功能的影响在很大程度上尚未被探索。通常建议采用卵母细胞冷冻保存和卵巢移位等策略来保障未来的生育能力。方法：本研究介绍了局部晚期骶骨软骨肉瘤碳离子放射治疗后成功妊娠的开创性病例。结果：多学科方法促进了卵巢和子宫的移位结论：患者在完成癌症治疗后获得了最佳的肿瘤反应，并产下健康婴儿。