ObjectiveIn this study leukocyte, lymphocyte, neutrophil, platelet count, mean platelet volume (MPV), neutrophil/lymphocyte (NLR) ratio and platelet/lymphocyte ratio (PLR) were retrospectively evaluated in patients with idiopathic acute anterior uveitis.Materials and methodsMedical records were retrospectively reviewed from March 2016 to February 2020. Fifty patients (25 men and 25 women) and as the control group, 50 healthy volunteers (25 males and 25 females) were included in this study. Blood samples of the patients were taken before starting treatment. A complete ophthalmological examination, including corrected visual acuity, tonometry, slit lamp and fundus examination, was performed in all patients. Gender, age, leukocyte, neutrophil, lymphocyte, platelet, MPV, PLR, and NLR values of the patients were recorded.ResultsIn this study, a statistically significant difference was found in leukocyte ( p < .001), neutrophil ( p < .001), platelet ( p < .001), NLR ( p < .001) and PLR ( p < .001) values. No significant difference was found between the two groups in terms of lymphocyte count ( p = .063) and in the MPV value ( p = .051). Leukocyte, neutrophil, platelet count, NLR, and PLR values were higher in the uveitis group compared to the control group. In the receiver operating characteristic (ROC) curve analysis, the area under the curve (AUC) for NLR was 0.805, with a sensitivity of 56.0% and a specificity of 98.0%. The AUC for PLR was 0.657, with a sensitivity of 52.0% and a specificity of 98.0%.ConclusionIn this retrospective study, leukocyte, neutrophil, platelet count, PLR, and NLR levels were significantly higher in patients with idiopathic acute anterior uveitis compared to the control group. These blood parameters are useful as diagnostic markers and can be used in early diagnosis.

中文翻译：

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中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值及平均血小板体积与特发性急性前葡萄膜炎的关系

目的回顾性分析特发性急性前葡萄膜炎患者的白细胞、淋巴细胞、中性粒细胞、血小板计数、平均血小板体积（MPV）、中性粒细胞/淋巴细胞比值（NLR）和血小板/淋巴细胞比值（PLR）。回顾性分析2016年3月至2020年2月期间的情况。本研究纳入了50名患者（25名男性和25名女性）以及50名健康志愿者（25名男性和25名女性）作为对照组。在开始治疗之前采集患者的血样。所有患者均进行了完整的眼科检查，包括矫正视力、眼压测量、裂隙灯和眼底检查。记录患者的性别、年龄、白细胞、中性粒细胞、淋巴细胞、血小板、MPV、PLR 和 NLR 值。 结果在本研究中，白细胞 ( p < .001)、中性粒细胞 ( p < .001) 存在统计学显着性差异)、血小板 (p < .001)、NLR (p < .001) 和 PLR (p < .001) 值。两组之间在淋巴细胞计数 (p = .063) 和 MPV 值 (p = .051) 方面没有发现显着差异。与对照组相比，葡萄膜炎组白细胞、中性粒细胞、血小板计数、NLR 和 PLR 值较高。在受试者工作特征（ROC）曲线分析中，NLR的曲线下面积（AUC）为0.805，敏感性为56.0%，特异性为98.0%。PLR 的 AUC 为 0.657，敏感性为 52.0%，特异性为 98.0%。 结论 在这项回顾性研究中，特发性急性前葡萄膜炎患者的白细胞、中性粒细胞、血小板计数、PLR 和 NLR 水平显着高于正常患者。控制组。这些血液参数可用作诊断标志物，可用于早期诊断。