The aetiopathogenesis of chronic obstructive pulmonary disease (COPD) remains unclear. The aim of our study was to determine the possible influence of Ascaris lumbricoides on the development of chronic pulmonary aspergillosis (CPA) in patients with COPD. The prevalence of A. lumbricoides in patients with COPD with CPA (19.05%) was significantly higher than that in those without (9.20%) and controls (4.9%) ( p < 0.05). Trends in levels of Interleukin-1β and of tumour necrosis factor α suggest ascariasis increases susceptibility to Aspergillus sp. in patients with COPD and can be considered an additional risk factor for CPA.

中文翻译：

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蛔虫感染对 COPD 患者慢性肺曲霉病发展的影响

慢性阻塞性肺疾病（COPD）的发病机制仍不清楚。我们研究的目的是确定蛔虫对 COPD 患者慢性肺曲霉病 (CPA) 发展的可能影响。患有 CPA 的 COPD 患者中蛔虫的患病率 (19.05%) 显着高于没有 CPA 的患者 (9.20%) 和对照组 (4.9%) ( p < 0.05)。Interleukin-1β 和肿瘤坏死因子 α 水平的趋势表明蛔虫病增加了对曲霉属的易感性。慢性阻塞性肺病 (COPD) 患者中，可被视为 CPA 的另一个危险因素。