IntroductionUnfractionated heparin remains the mainstay of anticoagulation therapy during extracorporeal membrane oxygenation (ECMO) maintenance. However, its continued use in clinical practice exposes patients to the risk of developing heparin-induced thrombocytopenia (HIT).Case ReportA 50-year-old male was diagnosed with multiple thromboses, including an intracardiac thrombi, accompanied by HIT during ECMO after cardiogenic shock related to acute myocardial infarction. The patient was successfully treated with new oral anticoagulants (NOAC), without significant complications.DiscussionHIT during ECMO resulting in multiple thromboses is rare. To our knowledge, this is the first reported case of NOAC use in this context.ConclusionAlthough thrombocytopenia and thrombosis can occur for various reasons during ECMO maintenance, it is important to consider HIT as a potential cause. NOACs can be considered as a therapeutic option.

中文翻译：

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多发性血栓，包括心内血栓，在 ECMO 成功治疗 NOAC 期间伴有 HIT：一例病例报告

简介普通肝素仍然是体外膜肺氧合 (ECMO) 维持期间抗凝治疗的支柱。然而，在临床实践中继续使用它会使患者面临发生肝素诱导的血小板减少症（HIT）的风险。病例报告一名50岁男性在心源性休克后进行ECMO时被诊断出多发血栓，包括心内血栓，并伴有HIT与急性心肌梗塞有关。该患者使用新型口服抗凝剂（NOAC）成功治疗，未出现明显并发症。讨论 ECMO 期间发生 HIT 导致多发血栓的情况很少见。据我们所知，这是第一例报告的在这种情况下使用 NOAC 的病例。 结论 尽管 ECMO 维持期间可能因各种原因发生血小板减少和血栓形成，但重要的是要将 HIT 视为潜在原因。NOAC 可被视为一种治疗选择。