Introduction:Currently, assessing ADHD treatment response to stimulants relies on rating scales and subjective questionnaires and sometimes a CPT. Such tools fall short of objective, quantifiable measurement of effect, especially in natural settings and can result in inconsistent treatment.Method:We report results from two studies using a novel proof-of-concept approach. A preliminary trial of 10 individuals used a high-fidelity eye tracker; a second study of 100 individuals used webcams at the participants’ homes.Results:Both studies evaluated stimulant effect using reading behavior analysis, being an ADHD symptom that stimulants affect and a major symptom patients want to improve. Both showed a significant change in reading behavior related to medication state, suggesting a clear, objective measure of stimulant effect.Conclusion:Using ubiquitous hardware, investigators created a user-friendly treatment assessment platform where individuals can collect their own objective data within minutes in any setting where they have access to a web camera and computer.

中文翻译：

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客观评估兴奋剂对多动症患者注意力的影响

简介：目前，评估 ADHD 对兴奋剂的治疗反应依赖于评级量表和主观问卷，有时还依赖于 CPT。此类工具无法客观、可量化地衡量效果，尤其是在自然环境中，并且可能导致治疗不一致。方法：我们使用新颖的概念验证方法报告了两项研究的结果。对 10 个人进行的初步试验使用了高保真眼动仪；第二项研究对 100 人进行了研究，在参与者家中使用了网络摄像头。 结果：两项研究都使用阅读行为分析来评估兴奋剂的效果，这是兴奋剂影响的 ADHD 症状，也是患者希望改善的主要症状。两者都显示出与药物状态相关的阅读行为发生了显着变化，这表明了对刺激效果的清晰、客观的衡量。结论：利用无处不在的硬件，研究人员创建了一个用户友好的治疗评估平台，个人可以在几分钟内以任何方式收集自己的客观数据。设置他们可以访问网络摄像头和计算机的位置。