当前位置：
X-MOL 学术
›
Epilepsy Behav.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The burden of epilepsy on long-term outcome of genetic developmental and epileptic encephalopathies: A single tertiary center longitudinal retrospective cohort study
Epilepsy & Behavior ( IF 2.6 ) Pub Date : 2024-02-08 , DOI: 10.1016/j.yebeh.2024.109670 Mario Mastrangelo , Filippo Manti , Giacomina Ricciardi , Rossella Bove , Carlo Greco , Manuela Tolve , Francesco Pisani
Epilepsy & Behavior ( IF 2.6 ) Pub Date : 2024-02-08 , DOI: 10.1016/j.yebeh.2024.109670 Mario Mastrangelo , Filippo Manti , Giacomina Ricciardi , Rossella Bove , Carlo Greco , Manuela Tolve , Francesco Pisani
This retrospective cohort analysis highlighted neurodevelopmental outcome predictors of genetic developmental and epileptic encephalopathies (DEE). Patients’ demographic, clinical and molecular genetics data were collected. All patients underwent clinical, developmental, and neuropsychological assessments. We recruited 100 participants (53 males, 47 females) with a mean follow-up lasting 10.46 ± 8.37 years. Age at seizure-onset, EEG maturation/organization, duration of epilepsy, occurrence of status epilepticus, age at the introduction and number of ASMs used are reliable predictors of long-term outcomes in patients with genetic DEE.
更新日期：2024-02-08
京公网安备 11010802027423号