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Investigation of the Use of Gelatine-Glycerine and Gelatine-Polyvinyl Alcohol Mixtures as Tissue Consistency Preservatives in Cadavers Fixed with Modified SEFS Solution
Annals of Anatomy ( IF 2.2 ) Pub Date : 2024-02-24 , DOI: 10.1016/j.aanat.2024.152235
Zeynep İpek Oruç , Erkut Turan

This study aimed to improve the effectiveness of SEFS, a fixing solution composed of soap and ethanol. This was achieved by modifying the formulation of SEFS. Additionally, this study aimed to preserve the consistency of organs by perfusing cadavers with mixtures of gelatine-glycerin (gelatine-Gls) and gelatine-polyvinyl alcohol (gelatine-PVA) through vascular access. The modified SEFS embalmed cadavers were divided into two groups: Group I was treated with gelatine-glycerin, and Group II was treated with gelatine-polyvinyl alcohol and each group comprised of two goats and three rabbits. Over one year, cadavers were objectively assessed for hardness, colour, and joint range of motion. Additionally, the cadavers were subjectively evaluated after dissection and palpation. For the modified SEFS embalmment haptic and optic examinations of the muscles revealed they maintained a vivid colour tone, closely resembling their natural colour. The thoracic organs displayed natural colour, with the lungs retaining their shape without collapse. Notably, the walls of the atrium and ventricles of the heart remained intact without inward collapse. The use of gelatine-PVA yielded better outcomes than gelatine-Gls in preserving the volumes of both chest and abdominal organs. This was particularly evident in the heart, lungs, liver, spleen, and kidney.

中文翻译:

使用明胶-甘油和明胶-聚乙烯醇混合物作为用改良 SEFS 溶液固定的尸体的组织稠度防腐剂的研究

本研究旨在提高 SEFS(一种由肥皂和乙醇组成的固定溶液)的有效性。这是通过修改 SEFS 的配方来实现的。此外,本研究旨在通过血管通路向尸体灌注明胶-甘油(明胶-Gls)和明胶-聚乙烯醇(明胶-PVA)混合物,以保持器官的一致性。将改良SEFS防腐尸体分为两组:第一组用明胶-甘油处理,第二组用明胶-聚乙烯醇处理,每组由两只山羊和三只兔子组成。在一年多的时间里,对尸体的硬度、颜色和关节活动范围进行了客观评估。此外,在解剖和触诊后对尸体进行主观评估。对于改良的 SEFS 防腐剂,肌肉的触觉和光学检查显示它们保持了鲜艳的色调,与自然颜色非常相似。胸部器官呈现自然颜色,肺部保持其形状,没有塌陷。值得注意的是,心房和心室的壁保持完整,没有向内塌陷。在保存胸部和腹部器官的体积方面,使用明胶-PVA 比使用明胶-Gls 效果更好。这在心、肺、肝、脾和肾中尤其明显。
更新日期:2024-02-24
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