This review aims to provide a comprehensive summary of the latest research progress regarding the relationship between epilepsy and circular RNA (circRNA). Relevant literature from the PubMed database was meticulously searched and reviewed. The selected articles focused on investigating the association between epilepsy and circRNA, including studies on expression patterns, diagnostic markers, therapeutic targets, and functional mechanisms. Epilepsy, characterized by recurrent seizures, is a neurological disorder. Numerous studies have demonstrated significant alterations in the expression profiles of circRNA in epileptic brain tissues, animal models, and peripheral blood samples. These differential expressions of circRNA are believed to be closely linked with the occurrence and development of epilepsy. Moreover, circRNA has shown promising potential as diagnostic markers for epilepsy, as well as prognostic indicators for predicting disease outcomes. Furthermore, circRNA has emerged as a potential therapeutic target for epilepsy treatment, offering prospects for gene therapy interventions. The dysregulation of circRNA expression in epilepsy suggests its potential involvement in the pathogenesis and progression of this disorder. Identifying specific circRNA molecules associated with epilepsy may pave the way for novel diagnostic approaches and therapeutic strategies. However, further investigations are imperative to elucidate the precise functional mechanisms of circRNA in epilepsy and validate its clinical utility.

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癫痫与circRNA关系的研究进展

本文旨在全面总结癫痫与环状RNA（circRNA）关系的最新研究进展。仔细检索和审查了 PubMed 数据库中的相关文献。入选文章重点研究癫痫与circRNA之间的关联，包括表达模式、诊断标志物、治疗靶点和功能机制的研究。癫痫是一种神经系统疾病，以反复发作为特征。大量研究表明，癫痫脑组织、动物模型和外周血样本中 circRNA 的表达谱发生显着变化。 circRNA的这些差异表达被认为与癫痫的发生和发展密切相关。此外，circRNA 作为癫痫的诊断标记物以及预测疾病结果的预后指标显示出巨大的潜力。此外，circRNA已成为癫痫治疗的潜在治疗靶点，为基因治疗干预提供了前景。癫痫中 circRNA 表达的失调表明其可能参与该疾病的发病机制和进展。鉴定与癫痫相关的特定 circRNA 分子可能为新的诊断方法和治疗策略铺平道路。然而，还需要进一步的研究来阐明 circRNA 在癫痫中的精确功能机制并验证其临床效用。