Three-component reaction between aryl glyoxals, aryl amines, and guanidine afforded ,-di (-amino aryl ketone) derivatives. This method include two C–N bonds formation in a one-pot and single synthetic step in neutral and simple reaction conditions. All reactions were conducted in EtOH as solvent at reflux conditions without using any catalyst, and the stable products were obtained in high yields. The structures of all products were proved by H and C NMR, IR spectral and elemental analysis data.

中文翻译：

---

在胍作为氮源存在下，由芳基乙二醛和芳基胺一锅法合成 N,N-二（α-氨基芳基酮）

芳基乙二醛、芳基胺和胍之间的三组分反应得到，，-二(-氨基芳基酮)衍生物。该方法包括在中性且简单的反应条件下一锅法和单一合成步骤中形成两个C-N键。所有反应均以EtOH为溶剂，在回流条件下进行，不使用任何催化剂，并且以高收率获得了稳定的产物。所有产物的结构均经核磁共振氢谱、碳谱、红外光谱和元素分析数据证实。