Many studies suggest that tumor microbiome closely relates to the oncogenesis and anti-tumor responses in multiple cancer types (e.g., colorectal cancer (CRC), breast cancer, lung cancer and pancreatic cancer), thereby raising an emerging research area of bacteria-related tumor therapy. Nanomaterials have long been used for both cancer and bacterial infection treatment, holding great potential for bacteria-related tumor therapy. In this review, we summarized recent progress in nanomaterials for bacteria-related tumor therapy. We focus on the types and mechanisms of pathogenic bacteria in the development and promotion of cancers and emphasize how nanomaterials work. We also briefly discuss the design principles and challenges of nanomaterials for bacteria-related tumor therapy. We hope this review can provide some insights into this emerging and rapidly growing research area.

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纳米材料用于细菌相关肿瘤治疗的最新进展

许多研究表明，肿瘤微生物组与多种癌症类型（例如结直肠癌（CRC）、乳腺癌、肺癌和胰腺癌）的肿瘤发生和抗肿瘤反应密切相关，从而引发了细菌相关肿瘤的新兴研究领域治疗。纳米材料长期以来一直用于癌症和细菌感染治疗，在细菌相关肿瘤治疗方面具有巨大潜力。在这篇综述中，我们总结了纳米材料用于细菌相关肿瘤治疗的最新进展。我们重点研究致病菌在癌症发生和促进过程中的类型和机制，并强调纳米材料的工作原理。我们还简要讨论了用于细菌相关肿瘤治疗的纳米材料的设计原理和挑战。我们希望这篇综述能够为这个新兴且快速发展的研究领域提供一些见解。