Sodium butyrate ameliorates high glucose-suppressed neuronal mitophagy by restoring PRKN expression via inhibiting the RELA-HDAC8 complex,Autophagy

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Sodium butyrate ameliorates high glucose-suppressed neuronal mitophagy by restoring PRKN expression via inhibiting the RELA-HDAC8 complex
Autophagy ( IF 13.3 ) Pub Date : 2024-02-26 , DOI: 10.1080/15548627.2024.2323785
Ji Hyeon Cho ₁ , Chang Woo Chae ₁ , Jae Ryong Lim ₁ , Young Hyun Jung ₁ , Su Jong Han ₁ , Jee Hyeon Yoon ₁ , Ji Yong Park ₁ , Ho Jae Han ₁

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Damaged mitochondria accumulation in diabetes is one of the main features that contribute to increased incidence of cognitive impairment by inducing apoptosis. Butyrate is a major metabolite produc...

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