Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A randomized, open-label, 5-period crossover study evaluating the pharmacokinetics and safety of a single dose of intranasal dihydroergotamine (DHE) powder (STS101), intramuscular DHE mesylate, and liquid nasal spray DHE in healthy adults
Headache ( IF 5 ) Pub Date : 2024-02-27 , DOI: 10.1111/head.14685 Richard B. Lipton 1 , Detlef Albrecht 2 , Maria Bermudez 3 , Jerry Hu 4 , Elizabeth Hussey 4 , Jeff Levy 3
Headache ( IF 5 ) Pub Date : 2024-02-27 , DOI: 10.1111/head.14685 Richard B. Lipton 1 , Detlef Albrecht 2 , Maria Bermudez 3 , Jerry Hu 4 , Elizabeth Hussey 4 , Jeff Levy 3
Affiliation
To compare the safety and pharmacokinetics (PK) of dihydroergotamine (DHE) after administration of intranasal DHE powder (STS101), liquid nasal spray (LNS) DHE mesylate, and intramuscular (IM) DHE mesylate injection in healthy participants.
中文翻译：
一项随机、开放、5阶段交叉研究，评估单剂量鼻内二氢麦角胺 (DHE) 粉末 (STS101)、肌肉注射 DHE 甲磺酸盐和液体鼻喷雾剂 DHE 在健康成人中的药代动力学和安全性
比较健康受试者给予鼻内 DHE 粉末 (STS101)、液体鼻喷雾剂 (LNS) DHE 甲磺酸盐和肌内 (IM) DHE 甲磺酸盐注射液后二氢麦角胺 (DHE) 的安全性和药代动力学 (PK)。
更新日期：2024-02-27
中文翻译：
一项随机、开放、5阶段交叉研究，评估单剂量鼻内二氢麦角胺 (DHE) 粉末 (STS101)、肌肉注射 DHE 甲磺酸盐和液体鼻喷雾剂 DHE 在健康成人中的药代动力学和安全性
比较健康受试者给予鼻内 DHE 粉末 (STS101)、液体鼻喷雾剂 (LNS) DHE 甲磺酸盐和肌内 (IM) DHE 甲磺酸盐注射液后二氢麦角胺 (DHE) 的安全性和药代动力学 (PK)。
京公网安备 11010802027423号