: Delirium, an acute and fluctuating mental disturbance of attention, cognition, and consciousness, commonly occurs in acute stroke. Research on long-term outcomes of stroke patients experiencing delirium is limited, especially regarding cognitive and psychiatric symptoms. : As part of the Nor-COAST study, 373 patients were screened for delirium using the Confusion Assessment Method (CAM) in the acute phase of stroke. Patients were included in the mixed-model linear regression analyses if they had available data from the follow-ups at three, 18 or 36 months, totaling 334 (44.6% women, mean () age: 72.1 (12.5) years, 17 (5.1%) diagnosed with delirium). Global cognition was measured using the Montreal Cognitive Assessment (MoCA). Psychiatric symptoms were measured using the Hospital Anxiety and Depression Scale (HADS) and the Neuropsychiatric Inventory-Questionnaire (NPI-Q). : At three months, delirium was associated with a higher NPI-Q score (Mean () 2.9 (3.6) vs 1.4 (2.2)). At 18 and 36 months, delirium was associated with a lower MoCA score (Mean () 19.7 (6.6) vs 24.3 (5.0), and 20.6 (7.6) vs 24.6 (4.8)), higher HADS anxiety symptoms (5.0 (4.3) vs 3.3 (3.3), and 5.9 (4.1) vs 3.4 (3.6)), higher HADS depression symptoms (7.2 (4.7) vs 3.4 (3.3), and 6.6 (5.1) vs 3.7 (3.7)), and higher NPI-Q score (2.4 (4.4) vs 1.7 (2.3), 2.6 (4.5) vs 1.0 (1.9)). Delirium significantly predicted the psychiatric symptoms hallucinations and agitation. : Patients with delirium in the acute phase of stroke may be particularly vulnerable to developing cognitive and psychiatric symptoms in the chronic phase.

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急性中风中的谵妄与随着时间的推移认知和精神症状的增加有关：Nor-COAST 研究

：谵妄是一种注意力、认知和意识的急性波动性精神障碍，常见于急性中风。关于发生谵妄的中风患者的长期结果的研究是有限的，特别是在认知和精神症状方面。：作为 Nor-COAST 研究的一部分，使用混乱评估法 (CAM) 在中风急性期对 373 名患者进行了谵妄筛查。如果患者有 3、18 或 36 个月随访数据，则纳入混合模型线性回归分析，总计 334 名患者（44.6% 为女性，平均年龄：72.1（12.5）岁，17 岁（5.1）岁） %) 诊断为谵妄)。使用蒙特利尔认知评估（MoCA）来测量整体认知。使用医院焦虑和抑郁量表（HADS）和神经精神问卷调查表（NPI-Q）来测量精神症状。：三个月时，谵妄与较高的 NPI-Q 评分相关（平均值 () 2.9 (3.6) vs 1.4 (2.2)）。在 18 个月和 36 个月时，谵妄与较低的 MoCA 评分（平均 19.7 (6.6) vs 24.3 (5.0)、20.6 (7.6) vs 24.6 (4.8)）、较高的 HADS 焦虑症状（5.0 (4.3) vs 24.3 (5.0)）相关。 3.3 (3.3) 和 5.9 (4.1) 对比 3.4 (3.6))，更高的 HADS 抑郁症状（7.2 (4.7) 对比 3.4 (3.3) 和 6.6 (5.1) 对比 3.7 (3.7))，以及更高的 NPI-Q 评分（2.4 (4.4) 与 1.7 (2.3)、2.6 (4.5) 与 1.0 (1.9)）。谵妄显着预测了幻觉和激越等精神症状。：中风急性期出现谵妄的患者在慢性期可能特别容易出现认知和精神症状。