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Florisil as an efficient reagent for deprotection of tert-butyl carbamates, carbonates and esters
Tetrahedron ( IF 2.1 ) Pub Date : 2024-02-24 , DOI: 10.1016/j.tet.2024.133904
Cheng-Hang Liu , Mengyang Xu , Qiyun Luo , Ziyan Wang , Wenyue Tan , Xingzeng Zhao , Xiaodong Jia

Florisil (magnesium polysilicate) is an efficient and eco-friendly reagent for the deprotection of -butyl carbamates, carbonates, and ethers. Moderate to excellent yields could be achieved in the presence of other acid-sensitive groups. The separation of products is easy, and Florisil can be recycled several times without observing a decrease in yields.

中文翻译:

Florisil 作为氨基甲酸叔丁酯、碳酸酯和酯脱保护的有效试剂

Florisil(聚硅酸镁)是一种高效、环保的试剂,用于氨基甲酸丁酯、碳酸酯和醚的脱保护。在其他酸敏感基团存在的情况下可以实现中等至优异的产率。产品分离容易,弗罗里硅土可以多次循环利用,且收率不会下降。
更新日期:2024-02-24
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