In imaging of Yttrium-90 patients treated hepatic primary and metastatic cancers, bremsstrahlung photons produced in a wide energy range is used. However, the image quality depends on acquisition energy window. This research aimed energy window optimization for Yttrium-90 bremsstrahlung imaging and 48 patients with various types of cancer received radioembolization therapy were investigated. Patients were imaged using a GE Healthcare Optima NM/CT 640 series gamma camera system with a medium energy general-purpose (MEGP) collimator and planar images were acquired with 8 different energy windows in the 55–400 keV energy range. The data set, formed with the % FOV, contrast, and spatial resolution of image quality parameters calculated from these images, was statistically examined with ANOVA and Tukey tests. According to the visual evaluations and ANOVA/Tukey test results, it was statistically concluded that energy window of 90–110 keV is the optimal energy window while 60–400 keV energy ranges show the lowest image quality for Y-90 bremsstrahlung imaging.

中文翻译：

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钇90微球治疗后轫致辐射成像的能量窗口优化

在对治疗原发性肝癌和转移性肝癌的钇 90 患者进行成像时，使用了宽能量范围内产生的轫致辐射光子。然而，图像质量取决于采集能量窗口。这项研究旨在优化钇 90 轫致辐射成像的能量窗口，并对 48 名接受放射栓塞治疗的各种类型癌症患者进行了调查。使用带有中等能量通用 (MEGP) 准直器的 GE Healthcare Optima NM/CT 640 系列伽马相机系统对患者进行成像，并使用 55-400 keV 能量范围内的 8 个不同能量窗口采集平面图像。数据集由从这些图像计算出的图像质量参数的% FOV、对比度和空间分辨率组成，并通过方差分析和 Tukey 测试进行统计检查。根据视觉评估和ANOVA/Tukey测试结果，统计得出90-110 keV的能量窗口是最佳能量窗口，而60-400 keV能量范围显示Y-90轫致辐射成像的图像质量最低。