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Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants.
The Bone & Joint Journal ( IF 4.6 ) Pub Date : 2024-03-01 , DOI: 10.1302/0301-620x.106b3.bjj-2023-0814.r1
Mark R. J. Jenkinson 1 , Dominic R. M. Meek 1 , Rothwelle Tate 2 , Adrian Brady 3, 4 , Sandy MacMillan 5 , Helen Grant 6 , Susan Currie 2
Affiliation  

Elevated blood cobalt levels secondary to metal-on-metal (MoM) hip arthroplasties are a suggested risk factor for developing cardiovascular complications including cardiomyopathy. Clinical studies assessing patients with MoM hips using left ventricular ejection fraction (LVEF) have found conflicting evidence of cobalt-induced cardiomyopathy. Global longitudinal strain (GLS) is an echocardiography measurement known to be more sensitive than LVEF when diagnosing early cardiomyopathies. The extent of cardiovascular injury, as measured by GLS, in patients with elevated blood cobalt levels has not previously been examined.

中文翻译:

因金属对金属髋关节植入物继发血液钴水平升高的患者,心脏功能可能会受到损害。

金属对金属 (MoM) 髋关节置换术继发的血钴水平升高是发生心血管并发症(包括心肌病)的一个危险因素。使用左心室射血分数 (LVEF) 评估 MoM 髋关节患者的临床研究发现了钴诱发心肌病的相互矛盾的证据。整体纵向应变 (GLS) 是一种超声心动图测量方法,在诊断早期心肌病时比 LVEF 更敏感。此前尚未对血液钴水平升高的患者通过 GLS 测量的心血管损伤程度进行过检查。
更新日期:2024-03-01
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