Polycystic ovary syndrome (PCOS) is one of the most common disorders among women in modern societies. A variety of factors can contribute to the development of PCOS. These women often exhibit high insulin resistance (IR), hyperandrogenism, irregular periods, and infertility. Dysbiosis of the gut microbiota (GMB) in women with PCOS has attracted the attention of many researchers. Porphyromonas spp., B. coprophilus, and F. prausnitzii are found in higher numbers in the gut of women with PCOS. Short-chain fatty acids (SCFAs), produced by the intestinal microbiota through fermentation, play an essential role in regulating metabolic activities and are helpful in reducing insulin resistance and improving PCOS symptoms. According to studies, the bacteria producing SCFAs in the gut of these women are less abundant than in healthy women. The effectiveness of using probiotic supplements has been proven to improve the condition of women with PCOS. Daily consumption of probiotics improves dysbiosis of the intestinal microbiome and increases the production of SCFAs.

多囊卵巢综合症（PCOS）是现代社会女性最常见的疾病之一。多种因素可能导致多囊卵巢综合症的发生。这些女性经常表现出高胰岛素抵抗（IR）、雄激素过多症、月经不规律和不孕症。多囊卵巢综合症女性肠道菌群（GMB）的失调引起了许多研究人员的关注。患有多囊卵巢综合症的女性肠道中发现较多的卟啉单胞菌、嗜粪杆菌和普拉梭菌。短链脂肪酸（SCFA）由肠道菌群通过发酵产生，在调节代谢活动中发挥着重要作用，有助于减少胰岛素抵抗和改善多囊卵巢综合症症状。研究表明，这些女性肠道中产生 SCFA 的细菌数量低于健康女性。已证明使用益生菌补充剂可以有效改善患有多囊卵巢综合症的女性的状况。每日摄入益生菌可以改善肠道微生物群的失调，并增加 SCFA 的产生。