Mandyphos-Pd has been proven to be a good chiral extractant to enantioseparate 3-chlorophenylglycine enantiomers with a separation factor of 2.64. However, this extractant is not suitable to enantioseparate other amino acids with separation factors of <2.0. The poor versatility has limited its practical application in chiral extraction.

中文翻译：

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通过引入具有不同空间和电子性质的基团提高Mandyphos-Pd配合物的对映选择性

Mandyphos-Pd 已被证明是一种良好的手性萃取剂，可用于分离 3-氯苯基甘氨酸对映体，分离因子为 2.64。然而，该萃取剂不适合分离因子<2.0的其他氨基酸的对映体分离。通用性差限制了其在手性萃取中的实际应用。