BackgroundSeveral recent studies have investigated the association between maternal diet during pregnancy and wheezing or asthma in children. However, whether a specific dietary pattern during pregnancy protects children from wheezing or atopic diseases remains unclear. This study investigated the association between The Alternative Healthy Eating Index for Pregnancy (AHEI‐P), the Dietary Inflammatory Index (DII), and the risk for wheezing and atopic eczema in children during the first year of life.MethodsThis study included 1330 mother–child pairs who attended the Kuopio Birth Cohort (KuBiCo) study and had dietary information during the last trimester and information on children's health in the first year of life. AHEI‐P and DII indicate a healthy diet and dietary inflammation potential during pregnancy. The AHEI‐P and DII were compared with reported wheezing and doctor‐diagnosed atopic eczema in children during the first year of life.ResultsNeither AHEI‐P nor DII is associated with wheezing or atopic eczema in children when analyzed by continuous variables and by tertiles. The odds ratio (95% CI) for AHEI‐P and wheezing was 0.99 (0.98–1.01), for AHEI‐P and atopic eczema1.01 (0.99–1.02), for DII and wheezing 1.02 (0.95–1.09), and for DII and atopic eczema 0.97 (0.91–1.04).ConclusionIn this cohort study, AHEI‐P and DII during pregnancy were not associated with wheezing or atopic eczema in the offspring during the first year of life.

中文翻译：

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母亲饮食指数与幼儿期喘息或特应性湿疹无关

背景最近的几项研究调查了母亲怀孕期间的饮食与儿童喘息或哮喘之间的关联。然而，怀孕期间的特定饮食模式是否可以保护儿童免受喘息或特应性疾病的侵害仍不清楚。这项研究调查了妊娠期替代健康饮食指数 (AHEI-P)、膳食炎症指数 (DII) 与儿童第一年出现喘息和特应性湿疹的风险之间的关系。方法这项研究包括 1330 名母亲——参加库奥皮奥出生队列 (KuBiCo) 研究并了解妊娠最后三个月的饮食信息以及儿童第一年健康信息的儿童对。AHEI-P 和 DII 表明孕期健康饮食和饮食炎症的可能性。将 AHEI-P 和 DII 与儿童一岁期间报告的喘息和医生诊断的特应性湿疹进行比较。结果通过连续变量和三分位数分析，AHEI-P 和 DII 均与儿童喘息或特应性湿疹无关。AHEI-P 和喘息的比值比 (95% CI) 为 0.99 (0.98–1.01)，AHEI-P 和特应性湿疹为 1.01 (0.99–1.02)，DII 和喘息为 1.02 (0.95–1.09)，而DII 和特应性湿疹 0.97 (0.91–1.04)。 结论 在这项队列研究中，妊娠期间的 AHEI-P 和 DII 与后代第一年的喘息或特应性湿疹无关。