Out-of-hospital cardiac arrest (OHCA) is a frequent and lethal condition with a yearly incidence of approximately 5000 in Denmark. Thirty-day survival is associated with the patient’s prodromal complaints prior to cardiac arrest. This paper examines the odds of 30-day survival dependent on the reported prodromal complaints among OHCAs witnessed by the emergency medical services (EMS). EMS-witnessed OHCAs in the Capital Region of Denmark from 2016-2018 were included. Calls to the emergency number 1-1-2 and the medical helpline for out-of-hours were analyzed according to the Danish Index; data regarding the OHCA was collected from the Danish Cardiac Arrest Registry. We performed multiple logistic regression to calculate the odds ratio (OR) of 30-day survival with adjustment for sex and age. We identified 311 eligible OHCAs of which 79 (25.4%) survived. The most commonly reported complaints were dyspnea ( = 209, OR 0.79 [95% CI 0.46: 1.36]) and ‘feeling generally unwell’ ( = 185, OR 1.07 [95% CI 0.63: 1.81]). Chest pain (OR 9.16 [95% CI 5.09:16.9]) and heart palpitations (OR 3.15 [95% CI 1.07:9.46]) had the highest ORs, indicating favorable odds for 30-day survival, while unresponsiveness (OR 0.22 [95% CI 0.11:0.43]) and blue skin or lips (OR 0.30, 95% CI 0.09, 0.81) had the lowest, indicating lesser odds of 30-day survival. Experiencing chest pain or heart palpitations prior to EMS-witnessed OHCA was associated with higher 30-day survival. Conversely, complaints of unresponsiveness or having blue skin or lips implied reduced odds of 30-day survival.

中文翻译：

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紧急医疗服务见证院外心脏骤停后的前驱症状和 30 天生存率

院外心脏骤停 (OHCA) 是一种常见且致命的疾病，在丹麦每年发生率约为 5000 例。三十天的生存率与患者心脏骤停前的前驱症状有关。本文根据紧急医疗服务 (EMS) 目睹的 OHCA 报告的前驱症状，研究了 30 天生存的几率。 2016 年至 2018 年丹麦首都地区 EMS 见证的 OHCA 也包括在内。根据丹麦指数对拨打紧急电话 1-1-2 和非工作时间医疗求助热线的情况进行了分析；有关 OHCA 的数据是从丹麦心脏骤停登记处收集的。我们进行了多重逻辑回归来计算调整性别和年龄后 30 天生存率 (OR)。我们确定了 311 名符合资格的 OHCA，其中 79 名 (25.4%) 幸存。最常见的主诉是呼吸困难（= 209，OR 0.79 [95% CI 0.46：1.36]）和“感觉普遍不适”（= 185，OR 1.07 [95% CI 0.63：1.81]）。胸痛 (OR 9.16 [95% CI 5.09:16.9]) 和心悸 (OR 3.15 [95% CI 1.07:9.46]) 的 OR 最高，表明 30 天生存率有利，而无反应 (OR 0.22 [95] % CI 0.11:0.43]）和蓝色皮肤或嘴唇（OR 0.30，95% CI 0.09，0.81）最低，表明 30 天生存率较低。在 EMS 见证的 OHCA 之前经历胸痛或心悸与较高的 30 天生存率相关。相反，抱怨反应迟钝或皮肤或嘴唇呈蓝色则意味着 30 天生存率降低。