ObjectivesPopulation‐based variations have been reported in permanent teeth eruption but only sparse literature exists on the same. A systematic review and meta‐analysis were performed to assess the global variations in eruption chronology of permanent teeth in children and adolescents and the role of sexes, jaws and classes of socio‐economic status (SES) on timing of eruption was explored.MethodsThe protocol for the systematic review was registered in PROSPERO. An extensive search of PubMed, EMBASE, Google Scholar, EBSCO, Cochrane library, and anthropology databases was carried out until April 2023. Additionally, grey literature search and hand‐searching of relevant key journals was done.ResultsOverall, 3797 cross‐sectional and longitudinal studies were retrieved from multiple databases. A total of 939, 191 participants were included from 80 studies of which, 41 were carried out in Asia, 26 in Europe, 5 in Africa, 4 in North America, and 4 in Oceania. The mandibular first molar eruption was found to be as early as 4.09 years while the maxillary second molar erupted as late as 13.45 years. Using a random effects model, 28 forest plots were generated. Meta‐regression interpreted tooth eruption to be earlier in females and in the mandible.ConclusionsThe findings of this study show that the ages of permanent teeth eruption was advanced in the European population followed by Africa and Asia.

中文翻译：

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恒牙萌出时间的全球变化：系统评价和荟萃分析

目的 恒牙萌出的人群差异已被报道，但相关文献却很少。我们进行了系统回顾和荟萃分析，以评估儿童和青少年恒牙萌出时间的全球差异，并探讨了性别、颌骨和社会经济地位（SES）类别对萌出时间的作用。系统评价已在 PROSPERO 中注册。截至 2023 年 4 月，对 PubMed、EMBASE、Google Scholar、EBSCO、Cochrane 图书馆和人类学数据库进行了广泛检索。此外，还进行了灰色文献检索和相关关键期刊的手工检索。结果总体而言，有 3797 个横断面和纵向文献研究是从多个数据库检索的。80 项研究共纳入 939 名受试者，其中 191 名参与者，其中 41 项在亚洲进行，26 项在欧洲进行，5 项在非洲进行，4 项在北美洲进行，4 项在大洋洲进行。下颌第一磨牙萌出最早为4.09年，上颌第二磨牙萌出最晚为13.45年。使用随机效应模型，生成了 28 个森林图。元回归解释女性和下颌的牙齿萌出较早。结论本研究的结果表明，欧洲人群的恒牙萌出年龄较早，其次是非洲和亚洲。