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Current advances on the therapeutic potential of scutellarin: an updated review
Natural Products and Bioprospecting Pub Date : 2024-03-04 , DOI: 10.1007/s13659-024-00441-3
Yifei Xie , Guotong Sun , Yue Tao , Wen Zhang , Shiying Yang , Li Zhang , Yang Lu , Guanhua Du

Scutellarin is widely distributed in Scutellaria baicalensis, family Labiatae, and Calendula officinalis, family Asteraceae, and belongs to flavonoids. Scutellarin has a wide range of pharmacological activities, it is widely used in the treatment of cerebral infarction, angina pectoris, cerebral thrombosis, coronary heart disease, and other diseases. It is a natural product with great research and development prospects. In recent years, with in-depth research, researchers have found that wild scutellarin also has good therapeutic effects in anti-tumor, anti-inflammatory, anti-oxidation, anti-virus, treatment of metabolic diseases, and protection of kidney. The cancer treatment involves glioma, breast cancer, lung cancer, renal cancer, colon cancer, and so on. In this paper, the sources, pharmacological effects, in vivo and in vitro models of scutellarin were summarized in recent years, and the current research status and future direction of scutellarin were analyzed.

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中文翻译:

灯盏乙素治疗潜力的最新进展:最新综述

黄芩苷广泛分布于唇形科黄芩和菊科金盏花中,属于黄酮类化合物。灯盏乙素具有广泛的药理活性,广泛用于治疗脑梗塞、心绞痛、脑血栓、冠心病等疾病。是一种具有巨大研究开发前景的天然产物。近年来,随着研究的深入,研究人员发现野生灯盏花乙素在抗肿瘤、抗炎、抗氧化、抗病毒、治疗代谢性疾病、保护肾脏等方面也具有良好的治疗作用。癌症治疗涉及胶质瘤、乳腺癌、肺癌、肾癌、结肠癌等。本文对近年来灯盏花乙素的来源、药理作用、体内外模型等进行了综述,并对灯盏花乙素的研究现状和未来方向进行了分析。

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更新日期:2024-03-04
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