This study aims to examine the mortality rate and trend of gastrointestinal cancers, particularly gastric cancer, as the leading cause of death among cancers in northern Iran over a 9-year period. In light of the changing incidence and mortality rates of cancer in Iran and around the world, the importance of these diseases in people’s lives, and the necessity of updating and monitoring the trend of cancer mortality, we have decided to report on the mortality trend of gastrointestinal cancers, based on crude and age-standardized rates. This study is a cross-sectional examination of deaths caused by gastrointestinal cancers in Babol city, Iran, between 2013 and 2021. Data was collected from the cause of death registration and classification system of Babol University of Medical Sciences. Population estimation was obtained from the latest census reports. The crude and age-standardized mortality rates and trends of the cancers were calculated. Overall, there were 1345 deaths from gastrointestinal cancers with an average age of 69.11 ± 14.25 years. The crude and age-standardized rates of these cancers rose from 24.1 to 20.1 per hundred thousand people in 2012 to 29.5 and 25.5 per hundred thousand people, respectively. This trend became more prevalent significantly with the increase of each decade of age for both men (P-value Trend = 0.002) and women (P-value Trend = 0.012). An analysis of gastrointestinal cancers revealed a decreasing trend for cancers of the small intestine, an increasing trend for cancers of the colon, pancreas, and gallbladder, and a stable trend for the remaining cancers over the study period. The age-standardized rate and the number of gastrointestinal cancers is rising, highlighting the importance of preventative measures such as screening, increasing public awareness, and appropriate diagnostic methods.

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调查伊朗北部巴博尔胃肠道癌症的死亡率趋势（2013-2021）

本研究旨在调查胃肠道癌症（特别是胃癌）的死亡率和趋势，该癌症是伊朗北部癌症死亡的主要原因，九年来。鉴于伊朗和世界各地癌症发病率和死亡率的变化、这些疾病在人们生活中的重要性以及更新和监测癌症死亡率趋势的必要性，我们决定报告胃肠道癌症，基于粗率和年龄标准化率。本研究对伊朗巴博尔市2013年至2021年间胃肠道癌症导致的死亡进行横断面调查。数据收集自巴博尔医科大学死因登记和分类系统。人口估计是从最新的人口普查报告中获得的。计算了癌症的粗死亡率和年龄标准化死亡率和趋势。总体而言，有1345人死于胃肠道癌症，平均年龄为69.11±14.25岁。这些癌症的粗略发病率和年龄标准化发病率从2012年的每10万人24.1例至20.1例分别上升至每10万人29.5例和25.5例。对于男性（P 值趋势 = 0.002）和女性（P 值趋势 = 0.012），这种趋势随着年龄的增长而变得更加普遍。对胃肠道癌症的分析显示，在研究期间，小肠癌症呈减少趋势，结肠癌、胰腺癌和胆囊癌呈增加趋势，而其余癌症则呈稳定趋势。胃肠道癌症的年龄标准化发病率和数量正在上升，凸显了筛查、提高公众意识和适当诊断方法等预防措施的重要性。