TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation,Cancer Biology & Therapy

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TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation
Cancer Biology & Therapy ( IF 3.6 ) Pub Date : 2024-03-06 , DOI: 10.1080/15384047.2024.2325126
Kaiwen Zhang ₁ , Xingyu Zheng ₁ , Yiqing Sun ₁ , Xinyu Feng ₁ , Xirong Wu ₂ , Wenlu Liu ₁ , Chao Gao ₁ , Ye Yan ₁ , Wenyan Tian ₁ , Yingmei Wang ₁

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Ovarian cancer (OC) is a form of gynecological malignancy that is associated with worse patient outcomes than any other cancer of the female reproductive tract. Topoisomerase II α (TOP2A) is common...

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