Prevention of acute respiratory illnesses (ARI) in children is a global health priority, as these remain a leading cause of pediatric morbidity and mortality throughout the world. As new products and strategies to prevent respiratory infections caused by important pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza, respiratory syncytial virus and pneumococcus are advancing, increasing evidence suggests that these and other respiratory viruses and pneumococci may exhibit interactions that are associated with altered colonization and disease dynamics. We aim to review recent data evaluating interactions between respiratory viruses and pneumococci in the upper respiratory tract and their potential impact on pneumococcal colonization patterns and disease outcomes.

中文翻译：

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呼吸道病毒感染对儿童鼻咽肺炎球菌定植动态的影响。

预防儿童急性呼吸道疾病 (ARI) 是全球健康的优先事项，因为这些疾病仍然是全世界儿科发病和死亡的主要原因。随着预防由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)、流感、呼吸道合胞病毒和肺炎球菌等重要病原体引起的呼吸道感染的新产品和策略的不断发展，越来越多的证据表明这些以及其他呼吸道病毒和肺炎球菌可能表现出与定植改变和疾病动态相关的相互作用。我们的目的是回顾最近的数据，评估上呼吸道呼吸道病毒和肺炎球菌之间的相互作用及其对肺炎球菌定植模式和疾病结果的潜在影响。