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Comprehensive review of status gelasticus: Diagnostic challenges and therapeutic insights
Epilepsy & Behavior ( IF 2.6 ) Pub Date : 2024-02-29 , DOI: 10.1016/j.yebeh.2024.109719
Antonio Gennaro Nicotera , Giulia Spoto , Greta Amore , Ambra Butera , Gabriella Di Rosa

Status gelasticus is a rare form of status epilepticus characterized by prolonged and/or clustered gelastic seizures. The review encompasses an analysis of cases reported in the literature, focusing on causes, clinical-electroencephalographic features, and therapeutic interventions. The study reveals the challenges in defining and understanding status gelasticus due to its diverse etiologies and limited reported cases. The association with hypothalamic hamartomas and other brain abnormalities underscores the importance of thorough evaluations. The review also discusses new treatments, including medications and less invasive surgeries. While progress has been made, the study points out challenges in diagnosing and managing this complex condition, highlighting the importance of ongoing research.

中文翻译:

凝胶状态的全面回顾:诊断挑战和治疗见解

凝胶持续状态是一种罕见的癫痫持续状态,其特征是长时间和/或聚集性凝胶发作。该综述包括对文献中报道的病例的分析,重点关注原因、临床脑电图特征和治疗干预措施。该研究揭示了由于其病因多样且报告病例有限而在定义和理解凝胶状态方面面临的挑战。与下丘脑错构瘤和其他大脑异常的关联强调了彻底评估的重要性。该评论还讨论了新的治疗方法,包括药物和微创手术。尽管取得了进展,但该研究指出了诊断和管理这种复杂疾病的挑战,强调了正在进行的研究的重要性。
更新日期:2024-02-29
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