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Total synthesis of natural alkaloids Schwarzinicines A-D
Tetrahedron ( IF 2.1 ) Pub Date : 2024-03-02 , DOI: 10.1016/j.tet.2024.133909
K. Annapurna , A. Venkat Narsaiah

Naturally occurring vasorelaxant alkaloids of 1,4-diarylbutanoidphenethylamines were synthesized successfully. Synthesis started from commercially available veratraldehyde, vanillin and piperonal. The important reactions involved in this synthesis are Corey-Fuchs, Eschweiler-Clarke, Henry reaction and lithium mediated carbon-carbon bond formation.

中文翻译:

天然生物碱Schwarzinicines AD的全合成

成功合成了天然存在的血管舒张生物碱1,4-二芳基丁苯乙胺。从市售的藜芦醛、香草醛和胡椒醛开始合成。该合成中涉及的重要反应是Corey-Fuchs、Eschweiler-Clarke、Henry反应和锂介导的碳-碳键形成。
更新日期:2024-03-02
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