The oxidative condensation of furfural (FUR) with alcohols is considered to be an effective approach for the preparation of liquid transport fuel precursors. In this work, the transition-metal-free oxidative condensation of FUR with alcohols has been introduced, which is achieved by NaOBu-promoted hydrogen auto-transfer, aerobic dehydrogenation and aldol condensation under atmospheric atmosphere. C3–C10 primary alcohols can be reacted with FUR smoothly to afford C8–C15 condensation products with good to excellent yields at 60–70 °C. Furthermore, the condensation of FUR and C4–C8 secondary alcohols are realized at 25∼40 °C to afford multiple condensation products owing to the multiple active sites of secondary alcohols.

中文翻译：

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碱促进生物质衍生的糠醛和醇的无过渡金属氧化缩合

糠醛（FUR）与醇的氧化缩合被认为是制备液体运输燃料前体的有效方法。在这项工作中，介绍了FUR与醇的无过渡金属氧化缩合，该反应是通过NaOBu促进的氢自转移、有氧脱氢和在大气气氛下羟醛缩合来实现的。 C3-C10 伯醇可以与 FUR 顺利反应，在 60-70 °C 下生成 C8-C15 缩合产物，收率良好至优异。此外，由于仲醇的多个活性位点，FUR和C4-C8仲醇的缩合在25～40℃下实现，得到多种缩合产物。