Conventional drug delivery systems are associated with various shortcomings, including low bioavailability and limited control over release. Biodegradable polymeric microparticles have emerged as versatile carriers in drug delivery systems addressing all these challenges. This comprehensive review explores the dynamic landscape of microparticles, considering the role of hydrophilic and hydrophobic materials. Within the continuously evolving domain of microparticle preparation methods, this review offers valuable insights into the latest advancements and addresses the factors influencing microencapsulation, which is pivotal for harnessing the full potential of microparticles. Exploration of the latest research in this dynamic field unlocks the possibilities of optimizing microencapsulation techniques to produce microparticles of desired characteristics and properties for different applications, which can help contribute to the ongoing evolution in the field of pharmaceutical science.

中文翻译：

---

揭示亲水性和疏水性聚合物在微粒系统中的潜力：加工技术的机遇和挑战

传统的药物递送系统存在多种缺点，包括生物利用度低和对释放的控制有限。可生物降解的聚合物微粒已成为药物输送系统中的多功能载体，解决了所有这些挑战。这篇综合综述探讨了微粒的动态景观，考虑了亲水性和疏水性材料的作用。在不断发展的微粒制备方法领域，这篇综述提供了对最新进展的宝贵见解，并解决了影响微胶囊化的因素，这对于充分发挥微粒的潜力至关重要。对这一动态领域最新研究的探索开启了优化微胶囊技术的可能性，以生产具有不同应用所需特征和性质的微粒，这有助于促进制药科学领域的持续发展。