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CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival
Autophagy ( IF 13.3 ) Pub Date : 2024-03-06 , DOI: 10.1080/15548627.2024.2309904
Prakash P. Praharaj 1 , Srimanta Patra 1 , Amruta Singh 1 , Debasna P. Panigrahi 1 , Hwa Y. Lee 2 , Mohammad F. Kabir 3 , Muhammad K. Hossain 4 , Samir K. Patra 5 , Birija S. Patro 6 , Shankargouda Patil 7 , Daniel J. Klionsky 8 , Han J. Chae 4, 9 , Sujit K. Bhutia 1
Affiliation  

Mitophagy involves the selective elimination of defective mitochondria during chemotherapeutic stress to maintain mitochondrial homeostasis and sustain cancer growth. Here, we showed that CLU (clus...

中文翻译:

CLU(簇蛋白)和 PPARGC1A/PGC1α 协调控制线粒体自噬和线粒体生物发生,促进口腔癌细胞存活

线粒体自噬涉及在化疗应激期间选择性消除有缺陷的线粒体,以维持线粒体稳态并维持癌症生长。在这里,我们展示了 CLU(clus...
更新日期:2024-03-07
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