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Use of potentially inappropriate medication for elderly patients in tertiary care hospital of Riyadh, Saudi Arabia
Saudi Pharmaceutical Journal ( IF 4.1 ) Pub Date : 2024-03-01 , DOI: 10.1016/j.jsps.2024.102015
Saleh A. Alanazi , Abdulrahman Al Amri , Mansour Almuqbil , Abdullah Alroumi , Merna Gamal Mohamed Alahmadi , Joud Obaid Ayesh Alotaibi , May Mohammed Sulaiman Alenazi , Wejdan Hassan Mossad Alahmadi , Alzahraa Hassan Saleh Al Bannay , Shorooq Khaled Ahmad Marai , Safier M. AlKhatham , Sarah Al-kanhal , Syed Mohammed Basheeruddin Asdaq

The elderly population is affected by chronic diseases and lifelong medication. The American Geriatrics Society (AGS) Beers Criteria is a comprehensive approach to medication usage in the older population to reduce potentially inappropriate medication (PIM) use. The purpose of this study was to assess the usage of PIMs in elderly patients upon discharge from tertiary care hospital settings in Riyadh, Saudi Arabia, using the AGS Beers Criteria 2019. The data was obtained from the medical records of 1237 patients (>65 years) who were discharged from medical or surgical wards at two hospitals affiliated with King Abdulaziz Medical City. The data was analyzed to determine the prevalence of PIM prescription, and the proportional odds of the independent factors influencing outcomes were estimated using ordinal regression analysis for criteria 1 and 2, while Binary regression analysis was conducted for criterion 3. There were approximately equal numbers of male and female participants in our study (male: 50.8 % vs. female: 49.2 %). One-third of the patients were above the age of 80 years, with 41 % being between the ages of 70 and 80 years. Moreover, almost 70 % of the samples had chronic illnesses. The overall prevalence of PIMs was 29.2 %, with 11 % of PIMs to be avoided in elderly patients and 17 % to be used with caution in the elderly, while disease-specific PIMs were identified in 1.2 % of the patients. The most common PIM class was proton pump inhibitors (44.41 %), and patients discharged from the surgical unit were more likely to be prescribed PIMs. Proton pump inhibitors (44.41 %) were the most inappropriately prescribed drug class, and patients discharged from the surgical unit were more likely to be prescribed PIMs. The study noticed that male gender, the presence of multiple diseases, and obesity are associated with more than one PIM prescription. There is a need to streamline the surgical department’s prescription procedure to eliminate prescription disparities. Prescription monitoring is recommended to avoid medication errors, particularly in patients who are taking multiple medications.

中文翻译:

沙特阿拉伯利雅得三级护理医院老年患者使用可能不适当的药物

老年人口受到慢性病和终身服药的影响。美国老年医学会 (AGS) 比尔标准是针对老年人群药物使用的综合方法,旨在减少潜在的不当药物 (PIM) 使用。本研究的目的是使用 2019 年 AGS Beers 标准评估从沙特阿拉伯利雅得三级护理医院出院的老年患者 PIM 的使用情况。数据来自 1237 名患者(> 65 岁)的医疗记录)从阿卜杜勒阿齐兹国王医疗城附属两家医院的内科或外科病房出院。分析数据以确定 PIM 处方的患病率,并使用标准 1 和 2 的序数回归分析估计影响结果的独立因素的比例优势,而标准 3 则进行二元回归分析。我们研究的男性和女性参与者(男性:50.8% vs. 女性:49.2%)。三分之一的患者年龄在80岁以上,其中41%的患者年龄在70岁至80岁之间。此外,近 70% 的样本患有慢性病。 PIM 的总体患病率为 29.2%,其中 11% 的老年患者应避免使用 PIM,17% 的老年患者需谨慎使用,而 1.2% 的患者中发现了疾病特异性 PIM。最常见的 PIM 类别是质子泵抑制剂 (44.41%),从手术室出院的患者更有可能服用 PIM。质子泵抑制剂(44.41%)是最不恰当的处方药物类别,从手术室出院的患者更有可能服用质子泵抑制剂。研究注意到,男性、多种疾病的存在以及肥胖与不止一种 PIM 处方相关。有必要简化外科部门的处方程序,以消除处方差异。建议监测处方以避免用药错误,特别是对于正在服用多种药物的患者。
更新日期:2024-03-01
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