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Changing hemostatic management in post‐partum hemorrhage
American Journal of Hematology ( IF 12.8 ) Pub Date : 2024-03-07 , DOI: 10.1002/ajh.27264
Agnès Rigouzzo 1 , Pierre‐Antoine Froissant 1 , Nicolas Louvet 1
Affiliation  

Early and fast assessment of hemostasis during postpartum hemorrhage (PPH) is essential to allow early characterization of coagulopathy, estimate bleeding severity and improve outcome. During PPH, fibrinogen decrease occurs earlier than other coagulation factors deficiency and hypofibrinogenemia is an early marker of PPH severity of progression. With good evidence in the context of PPH, point‐of‐care viscoelastic (VET) hemostatic assays have been shown to provide rapid assessment of hemostatic disorders, low fibrinogen levels, and allow VET‐guided fibrinogen replacement. Further studies are needed to define the thresholds for the other coagulation parameters.

中文翻译:

改变产后出血的止血治疗

产后出血 (PPH) 期间的早期、快速止血评估对于早期确定凝血障碍特征、估计出血严重程度和改善结局至关重要。在 PPH 期间,纤维蛋白原减少发生得早于其他凝血因子缺乏,低纤维蛋白原血症是 PPH 进展严重程度的早期标志。在 PPH 方面有充分的证据,护理点粘弹性 (VET) 止血测定已被证明可以快速评估止血障碍、低纤维蛋白原水平,并允许 VET 引导纤维蛋白原替代。需要进一步研究来定义其他凝血参数的阈值。
更新日期:2024-03-07
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