Investigating the correlation between blood cadmium levels, platelet characteristics, and susceptibility to coronary heart disease (CHD). Utilized NHANES 2005–2018 data with covariates such as age, sex, race, marital status, and socio-economic status. Blood cadmium served as the independent variable, while platelet count (PC) and mean platelet volume (MPV) were dependent variables. The average age of the participants was 68.77 ± 11.03 years, and 67.4% of them were male. The mean values for WBC, MPV, PC, and blood cadmium were 7.53 ± 3.36 × 10³ cells/µL, 11.33 ± 0.27fL, 57.61 ± 5.34 × 10³ cells/µL, and 2.58 ± 0.61 µg/L, respectively. Adjusting for other variables revealed increased MPV and PC with rising blood cadmium levels in cardiac patients, indicating a higher risk of CHD in those with elevated blood cadmium. The average age of the participants was 68.77 ± 11.03 years, and 67.4% of them were male. The mean values for WBC, MPV, PC, and blood cadmium were 7.53 ± 3.36 × 10³ cells/µL, 11.33 ± 0.27fL, 57.61 ± 5.34 × 10³ cells/µL, and 2.58 ± 0.61 µg/L, respectively. Adjusting for other variables revealed increased MPV and PC with rising blood cadmium levels in cardiac patients, indicating a higher risk of CHD in those with elevated blood cadmium. This study enhances understanding of how cadmium impacts platelet characteristics, contributing to increased CHD risk, providing insights for primary prevention strategies.

研究血镉水平、血小板特征和冠心病 (CHD) 易感性之间的相关性。利用 NHANES 2005-2018 数据以及年龄、性别、种族、婚姻状况和社会经济状况等协变量。血镉作为自变量，而血小板计数（PC）和平均血小板体积（MPV）是因变量。参与者的平均年龄为68.77±11.03岁，其中67.4%为男性。WBC、MPV、PC 和血镉的平均值分别为 7.53 ± 3.36 × 10 ^{3 个}细胞/μL、11.33 ± 0.27fL、57.61 ± 5.34 × 10 ^{3 个}细胞/μL 和 2.58 ± 0.61 µg/L。调整其他变量后发现，心脏病患者的 MPV 和 PC 随着血镉水平升高而增加，表明血镉升高的患者患 CHD 的风险较高。参与者的平均年龄为68.77±11.03岁，其中67.4%为男性。WBC、MPV、PC 和血镉的平均值分别为 7.53 ± 3.36 × 10 ^{3 个}细胞/μL、11.33 ± 0.27fL、57.61 ± 5.34 × 10 ^{3 个}细胞/μL 和 2.58 ± 0.61 µg/L。调整其他变量后发现，心脏病患者的 MPV 和 PC 随着血镉水平升高而增加，表明血镉升高的患者患 CHD 的风险较高。这项研究加深了人们对镉如何影响血小板特性、导致冠心病风险增加的理解，为一级预防策略提供了见解。