The choice of cleaning method is an important consideration for lengthening the serviceable time of facial prostheses as microbial organisms and biofilms could degrade facial prostheses and cause skin irritation. Whether microwave disinfection is a suitable cleaning method without degradation of the properties of a prosthesis is unclear. The purpose of this in vitro study was to measure the color stability of 6 commonly used facial silicone elastomers after microwave disinfection over a simulated 1.5-year period. Six different facial silicone elastomers: MDX4–4210, MDX4–4210/Type A, M511, A-2186, VST-50, and A-2000 were mixed with intrinsic silicone white opacifier (except for the control group) and subsequently combined with 4 silicone intrinsic pigment color groups: red (R), yellow (Y), burnt sienna (B), and a mixture of R+Y+B (M). The control group was a silicone elastomer without opacifier or pigment. Each of the 30 experimental groups consisted of 5 specimens (N=150). Five specimens were placed in a 250-mL Erlenmeyer flask filled with 160 mL of tap water. Seven flasks were then placed in a 660-W microwave oven. An exposure of 6 minutes was used according to the antimicrobial efficacy of microwave disinfection protocol on facial silicone prostheses with a final water temperature of 60 °C for 18 times (simulating 1.5 years of microwave disinfection with one 6-minute exposure monthly). A spectrophotometer was used to measure reflectance color change values (∆E). Color differences were calculated following CIELab (∆E*) and CIEDE2000 (∆E00) formulae. ∆E* and ∆E00 were statistically analyzed by a linear mixed effects model with 3 factors (silicone type, color shade, and time) using the R Statistical software program (α=.05). Both ∆E* and ∆E00 of all silicone elastomers studied were less than the visual perceptibility thresholds (∆E*<1.1 and E00<0.7) and were considered clinically acceptable (∆E*<3.0 and E00<2.1) after the 1.5-year simulation of microwave disinfection. Yellow and blue pigments had more effect on MDX4–4210 and M511, while red pigment had more effect on MDX4–4210, MDX4–4210/Type A, and M511 (P<.05). Nevertheless, the values were still below the perceptibility threshold (∆E*≤1.0 and E00<0.6). All 6 facial silicone elastomers maintained clinically acceptable color after 18 months of exposure to microwave disinfection.

中文翻译：

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面部硅胶假体的微波消毒，第 1 部分：颜色稳定性

清洁方法的选择是延长面部假体使用寿命的重要考虑因素，因为微生物和生物膜可能会降解面部假体并引起皮肤刺激。微波消毒是否是一种不会降低假体性能的合适清洁方法尚不清楚。这项体外研究的目的是测量 6 种常用面部有机硅弹性体在模拟 1.5 年期间微波消毒后的颜色稳定性。将六种不同的面部有机硅弹性体：MDX4–4210、MDX4–4210/A 型、M511、A-2186、VST-50 和 A-2000 与固有有机硅白色遮光剂（对照组除外）混合，然后与 4有机硅固有颜料颜色组：红色（R）、黄色（Y）、焦赭色（B）以及R+Y+B（M）的混合物。对照组是不含遮光剂或颜料的有机硅弹性体。30 个实验组每组由 5 个样本组成（N=150）。将五个样本放入装有 160 mL 自来水的 250 mL 锥形烧瓶中。然后将七个烧瓶放入 660 W 微波炉中。根据微波消毒方案对面部硅胶假体的抗菌效果，使用 6 分钟的暴露时间，最终水温为 60 °C，进行 18 次（模拟 1.5 年的微波消毒，每月一次 6 分钟的暴露）。使用分光光度计测量反射颜色变化值（ΔE）。色差根据 CIELab (ΔE*) 和 CIEDE2000 (ΔE00) 公式计算。使用 R 统计软件程序 (α=.05)，通过具有 3 个因素（有机硅类型、色调和时间）的线性混合效应模型对 ΔE* 和 ΔE00 进行统计分析。所有研究的有机硅弹性体的 ΔE* 和 ΔE00 均小于视觉感知阈值（ΔE*<1.1 和 E00<0.7），并且在 1.5- 后被认为是临床可接受的（ΔE*<3.0 和 E00<2.1）。年模拟微波消毒。黄色和蓝色颜料对 MDX4–4210 和 M511 的影响更大，而红色颜料对 MDX4–4210、MDX4–4210/A 型和 M511 的影响更大 (P<.05)。尽管如此，这些值仍然低于可感知阈值（ΔE*≤1.0 且 E00<0.6）。所有 6 种面部有机硅弹性体在暴露于微波消毒 18 个月后仍保持临床可接受的颜色。