Silicone-based passive samplers have emerged as powerful tools for assessing dermal and inhalation exposure to polycyclic aromatic hydrocarbons (PAHs) across diverse environmental settings. Despite their increasing application, the nascent stage of this methodology and the absence of standardized protocols have led to varied monitoring approaches, resulting in fragmented and incomparable datasets. This document offers a detailed meta-analysis of silicone-based samplers for PAHs evaluation, synthesizing findings from 32 studies to elucidate common sampler configurations, study setups, sample treatment protocols, and PAH detection rates. We propose a set of comprehensive guidelines aiming to standardize analytical practices and study designs within the field. Among the critical areas for improvement identified, the adoption of unified quantitation units and mitigation strategies for potential analyte losses during sample treatment stand out. These recommendations will enhance the reliability and comparability of future research, paving the way for more accurate risk evaluations related to PAH exposure.

中文翻译：

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人类通过硅基被动采样器接触多环芳烃：方法学方面和主要发现

基于硅胶的被动采样器已成为评估不同环境条件下多环芳烃 (PAH) 的皮肤和吸入暴露的强大工具。尽管其应用不断增加，但这种方法的初级阶段和标准化协议的缺乏导致了监测方法的多样化，导致数据集支离破碎且无法比较。本文件提供了用于 PAH 评估的有机硅采样器的详细荟萃分析，综合了 32 项研究的结果，以阐明常见的采样器配置、研究设置、样品处理方案和 PAH 检出率。我们提出了一套综合指南，旨在标准化该领域的分析实践和研究设计。在已确定的关键改进领域中，最突出的是采用统一的定量装置和减少样品处理过程中潜在分析物损失的策略。这些建议将提高未来研究的可靠性和可比性，为更准确地评估与多环芳烃暴露相关的风险铺平道路。