Remnant cholesterol (RC) is the cholesterol carried in lipoproteins derived from the catabolism of chylomicrons and very low-density lipoproteins. Evidence supporting the causal relationship of RC with atherosclerotic cardiovascular disease (ASVD) is accumulating rapidly. The number of impactful contributions to this field are increasing and provide a pathophysiological insight into the current residual cardiovascular risk beyond low-density cholesterol (LDL)-cholesterol (LDL-C). They also raise the question of whether RC should be used in prediction models and become the target of new therapeutic interventions. The intent of this review is to highlight the recent advances on the role of RC in atherogenesis and the validation of RC as a predictor of ASVD.

中文翻译：

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残余胆固醇在动脉粥样硬化性心血管疾病中的预测效用。

残余胆固醇（RC）是源自乳糜微粒和极低密度脂蛋白分解代谢的脂蛋白中携带的胆固醇。支持 RC 与动脉粥样硬化性心血管疾病 (ASVD) 因果关系的证据正在迅速积累。该领域有影响力的贡献数量不断增加，并为当前除低密度胆固醇 (LDL)-胆固醇 (LDL-C) 之外的残余心血管风险提供了病理生理学见解。他们还提出了 RC 是否应该用于预测模型并成为新的治疗干预措施目标的问题。本综述的目的是强调 RC 在动脉粥样硬化形成中的作用以及验证 RC 作为 ASVD 预测因子的最新进展。