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Avoidant/restrictive food intake disorder prevalence is high in children with gastroparesis and functional dyspepsia
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2024-03-08 , DOI: 10.1111/nmo.14777
Isha Kaul 1, 2, 3 , Helen Burton‐Murray 4, 5 , Salma Musaad 1, 2 , Yiming Mirabile 1, 2 , Danita Czyzewski 1, 3 , Miranda A. L. van Tilburg 6, 7, 8, 9, 10 , Andrew C. Sher 1, 3 , Bruno P. Chumpitazi 11 , Robert J. Shulman 1, 2, 3
Affiliation  

BackgroundAvoidant/restrictive food intake disorder (ARFID) prevalence in children with gastroparesis (Gp) and/or functional dyspepsia (FD) is unknown. We aimed to identify ARFID prevalence and trajectory over 2 months in children with Gp, FD, and healthy children (HC) using two screening questionnaires. We also explored the frequency of a positive ARFID screen between those with/without delayed gastric emptying or abnormal fundic accommodation.MethodsIn this prospective longitudinal study conducted at an urban tertiary care hospital, patients ages 10–17 years with Gp or FD and age‐ and gender‐matched HC completed two validated ARFID screening tools at baseline and 2‐month follow‐up: the Nine Item ARFID Screen (NIAS) and the Pica, ARFID, and Rumination Disorder Interview‐ARFID Questionnaire (PARDI‐AR‐Q). Gastric retention and fundic accommodation (for Gp and FD) were determined from gastric emptying scintigraphy.Key ResultsAt baseline, the proportion of children screening positive for ARFID on the NIAS versus PARDI‐AR‐Q was Gp: 48.5% versus 63.6%, FD: 66.7% versus 65.2%, HC: 15.3% versus 9.7%, respectively; p < 0.0001 across groups. Of children who screened positive at baseline and participated in the follow‐up, 71.9% and 53.3% were positive 2 months later (NIAS versus PARDI‐AR‐Q, respectively). A positive ARFID screen in Gp or FD was not related to the presence/absence of delayed gastric retention or abnormal fundic accommodation.Conclusions & InferencesARFID detected from screening questionnaires is highly prevalent among children with Gp and FD and persists for at least 2 months in a substantial proportion of children. Children with these disorders should be screened for ARFID.

中文翻译:

胃轻瘫和功能性消化不良儿童的回避/限制性食物摄入障碍患病率较高

背景 胃轻瘫 (Gp) 和/或功能性消化不良 (FD) 儿童中回避/限制性食物摄入障碍 (ARFID) 的患病率尚不清楚。我们的目的是使用两份筛查问卷来确定全科医生、FD 儿童和健康儿童 (HC) 儿童中 ARFID 的患病率和 2 个月内的轨迹。我们还探讨了患有/不患有胃排空延迟或胃底调节异常的患者之间 ARFID 筛查呈阳性的频率。 方法 在这项在城市三级护理医院进行的前瞻性纵向研究中,年龄为 10-17 岁的 Gp 或 FD 患者以及年龄和性别匹配的 HC 在基线和 2 个月的随访中完成了两种经过验证的 ARFID 筛查工具:九项 ARFID 筛查 (NIAS) 和异食癖、ARFID 和反刍障碍访谈 ARFID 问卷 (PARDI-AR-Q)。通过胃排空闪烁扫描确定胃潴留和胃底调节(Gp 和 FD)。 主要结果 在基线时,NIAS 与 PARDI-AR-Q 上 ARFID 筛查呈阳性的儿童比例为 Gp:48.5% 对 63.6%,FD:分别为 66.7% 与 65.2%,HC:15.3% 与 9.7%;p各组间 < 0.0001。在基线筛查呈阳性并参与随访的儿童中,2 个月后,71.9% 和 53.3% 呈阳性(分别为 NIAS 与 PARDI-AR-Q)。Gp 或 FD 中 ARFID 筛查呈阳性与是否存在延迟性胃潴留或胃底调节异常无关。结论与推论 从筛查问卷中检测到的 ARFID 在 Gp 和 FD 儿童中非常普遍,并且在一个病例中持续至少 2 个月。儿童比例相当大。患有这些疾病的儿童应该接受 ARFID 筛查。
更新日期:2024-03-08
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