Individuals with refractory ascites in the context of liver cirrhosis typically face an adverse prognosis. The transjugular intrahepatic portosystemic shunt (TIPS) is an efficacious intervention, but there is a lack of reliable tools for postoperative prognosis assessment. Previously utilized clinical biochemical markers, such as the serum albumin concentration (Alb), sodium (Na⁺) concentration, and serum creatinine (Scr), have limited predictive value. Therefore, the quest for novel, specific biomarkers to evaluate the post-TIPS prognosis in patients with liver cirrhosis and refractory ascites holds significant practical importance.

中文翻译：

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肝硬化腹水患者血清标志物与经颈静脉肝内门体分流术预后的相关性

肝硬化背景下难治性腹水的个体通常面临不良预后。经颈静脉肝内门体分流术（TIPS）是一种有效的干预措施，但缺乏可靠的术后预后评估工具。以前使用的临床生化标志物，例如血清白蛋白浓度（Alb）、钠（Na ⁺）浓度和血清肌酐（Scr），预测价值有限。因此，寻找新的、特异性的生物标志物来评估肝硬化和难治性腹水患者 TIPS 后的预后具有重要的实际意义。