Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression,Cancer Biology & Therapy

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Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression
Cancer Biology & Therapy ( IF 3.6 ) Pub Date : 2024-03-11 , DOI: 10.1080/15384047.2024.2323768
Yusi Wang _{1,

2} , Hongyan Zou _{1,

2} , Wei Ji _{1,

2} , Min Huang _{1,

2} , Benhui You _{1,

2} , Nan Sun _{1,

2} , Yuandong Qiao _{1,

2} , Peng Liu _{1,

2} , Lidan Xu _{1,

2} , Xuelong Zhang _{1,

2} , Mengdi Cai _{1,

2} , Ye Kuang ₃ , Songbin Fu _{1,

2} , Wenjing Sun _{1,

2} , Xueyuan Jia _{1,

2} , Jie Wu _{1,

2,

4}

Affiliation

Double minutes (DMs), extrachromosomal gene fragments found within certain tumors, have been noted to carry onco- and drug resistance genes contributing to tumor pathogenesis and progression. After...

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