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Acute Coronary Syndrome in Women: An Update
Current Cardiology Reports ( IF 3.7 ) Pub Date : 2024-03-11 , DOI: 10.1007/s11886-024-02033-6
Madeleine R. Alder , Kylie E. Adamek , Angela Lowenstern , Leah M. Raj , Kathryn J. Lindley , Nadia R. Sutton

Purpose of Review

The goal of this manuscript is to provide a concise summary of recent developments in the approach to and treatment of women with acute coronary syndrome (ACS).

Recent Findings

This review covers terminology updates relating to ACS and myocardial injury and infarction. Updates on disparities in recognition, treatments, and outcomes of women with ACS due to atherosclerotic coronary artery disease are covered. Other causes of ACS, including spontaneous coronary artery dissection and myocardial infarction with non-obstructive coronary artery disease are discussed, given the increased frequency in women compared with men. The review summarizes the latest on the unique circumstance of ACS in women who are pregnant or post-partum, including etiologies, diagnostic approaches, medication safety, and revascularization considerations.

Summary

Compared with men, women with ACS have unique risk factors, presentations, and pathophysiology. Treatments known to be effective for men with atherosclerosis-related ACS are also effective for women; further work remains on reducing the disparities in diagnosis and treatment. Implementation of multimodality imaging will improve diagnostic accuracy and allow for targeted medical therapy in the setting of myocardial infarction with non-obstructive coronary artery disease.



中文翻译:

女性急性冠状动脉综合征:最新进展

审查目的

本手稿的目的是简要总结女性急性冠脉综合征 (ACS) 的治疗方法和治疗的最新进展。

最近的发现

本综述涵盖了与 ACS 以及心肌损伤和梗塞相关的术语更新。报道了因动脉粥样硬化性冠状动脉疾病而患有 ACS 的女性在识别、治疗和结果方面的差异的最新情况。鉴于女性发生率高于男性,因此讨论了 ACS 的其他原因,包括自发性冠状动脉夹层和伴有非阻塞性冠状动脉疾病的心肌梗死。该综述总结了妊娠期或产后女性 ACS 独特情况的最新情况,包括病因、诊断方法、用药安全性和血运重建注意事项。

概括

与男性相比,女性 ACS 具有独特的危险因素、表现和病理生理学。已知对患有动脉粥样硬化相关 ACS 的男性有效的治疗方法对女性也有效;缩小诊断和治疗方面的差距仍需进一步努力。多模态成像的实施将提高诊断准确性,并允许在伴有非阻塞性冠状动脉疾病的心肌梗死的情况下进行针对性的药物治疗。

更新日期:2024-03-11
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