Amine-free phosphorylation of various alcohols was developed with 4-methylpyridine N-oxide in the presence of 4 Å molecular sieves at room temperature. This mild method gave various phosphorylated products in high yield and could be applied to acid- or base-sensitive substrates. Furthermore, this method was also effective for the chemoselective phosphorylation of diols or polyols.

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中文翻译：

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4-甲基吡啶 N-氧化物对醇进行有机催化的无胺 O-磷酸化

在室温下，在 4 Å 分子筛存在下，用 4-甲基吡啶N-氧化物对各种醇进行无胺磷酸化。这种温和的方法可以高产率地产生各种磷酸化产物，并且可以应用于酸或碱敏感的底物。此外，该方法对于二醇或多元醇的化学选择性磷酸化也有效。

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