Reprogramming of the genetic code allows the synthesis of proteins using new building blocks, thus opening the door to the development of a wider variety of medicines and biocatalysts; however, it is currently limited to α-amino acids. A new study has now reported the incorporation of β-linked and α,α-disubstituted monomers into a ribosome-synthesized protein.

中文翻译：

---

打破遗传密码扩展的僵局

遗传密码的重新编程允许使用新的构建模块合成蛋白质，从而为开发更广泛的药物和生物催化剂打开了大门；然而，目前仅限于α-氨基酸。一项新的研究现已报道将 β 连接和 α,α-二取代单体掺入核糖体合成的蛋白质中。