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Multifunctional MXene-Based Platforms for Soft and Bone Tissue Regeneration and Engineering
ACS Biomaterials Science & Engineering ( IF 5.8 ) Pub Date : 2024-03-11 , DOI: 10.1021/acsbiomaterials.3c01770
Siavash Iravani 1 , Ehsan Nazarzadeh Zare 2, 3 , Pooyan Makvandi 4, 5, 6
Affiliation  

MXenes and their composites hold great promise in the field of soft and bone tissue regeneration and engineering (TRE). However, there are challenges that need to be overcome, such as ensuring biocompatibility and controlling the morphologies of MXene-based scaffolds. The future prospects of MXenes in TRE include enhancing biocompatibility through surface modifications, developing multifunctional constructs, and conducting in vivo studies for clinical translation. The purpose of this perspective about MXenes and their composites in soft and bone TRE is to critically evaluate their potential applications and contributions in this field. This perspective aims to provide a comprehensive analysis of the challenges, advantages, limitations, and future prospects associated with the use of MXenes and their composites for soft and bone TRE. By examining the existing literature and research, the review seeks to consolidate the current knowledge and highlight the key findings and advancements in MXene-based TRE. It aims to contribute to the understanding of MXenes’ role in promoting soft and bone TRE, addressing the challenges faced in terms of biocompatibility, morphology control, and tissue interactions.

中文翻译:

用于软组织和骨组织再生和工程的多功能 MXene 平台

MXene 及其复合材料在软组织和骨组织再生与工程 (TRE) 领域具有广阔的前景。然而,仍有一些挑战需要克服,例如确保生物相容性和控制基于 MXene 的支架的形态。 MXene 在 TRE 中的未来前景包括通过表面修饰增强生物相容性、开发多功能结构以及进行临床转化的体内研究。关于 MXene 及其复合材料在软骨 TRE 中的观点的目的是批判性地评估它们在该领域的潜在应用和贡献。该观点旨在全面分析与使用 MXene 及其复合材料用于软骨 TRE 相关的挑战、优势、局限性和未来前景。通过审查现有文献和研究,该综述旨在巩固当前知识并强调基于 MXene 的 TRE 的主要发现和进展。它旨在帮助理解 MXenes 在促进软骨 TRE 中的作用,解决生物相容性、形态控制和组织相互作用方面面临的挑战。
更新日期:2024-03-11
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