Aflatoxins (AFs) are secondary metabolites produced by fungi, and they are deemed the most perilous mycotoxin and food safety predicament. The exposure of humans to mycotoxins transpires either directly through the consumption of contaminated agricultural commodities or indirectly through the ingestion of items derived from animals that have been nourished with tainted substances of animal origin. To ensure the detoxification of AFs in animal and plant food products and to mitigate the risks they pose to public health and the economy, diverse techniques (physical, chemical, and biological) have been subject to scrutiny. By altering and eradicating the molecular structure of the toxin, all of these approaches impede its transmission to the digestive system and potentially diminish the accessibility of toxins to the target tissue, ultimately eliminating them. Given the pervasive predicaments attributed to the contamination of foods and feeds by AFs, it is of utmost importance to urgently devise cost-effective and appropriate strategies to combat this hazard. This review highlights the concept of AFs, definitions, and benefits of postbiotics and their biological role in the detoxification of AFs, as well as their benefits in the food-pharmaceutical industry.

黄曲霉毒素（AFs）是真菌产生的次生代谢产物，被认为是最危险的霉菌毒素和食品安全困境。人类接触霉菌毒素的途径要么是直接通过食用受污染的农产品，要么是间接通过摄入用受污染的动物源物质喂养的动物制品。为了确保动植物食品中 AF 的解毒并减轻它们对公共卫生和经济造成的风险，多种技术（物理、化学和生物）受到了严格审查。通过改变和消除毒素的分子结构，所有这些方法都会阻止其传播到消化系统，并可能减少毒素进入目标组织的机会，最终消除它们。鉴于食品和饲料被AF污染所造成的普遍困境，迫切需要制定具有成本效益且适当的策略来应对这种危害。本综述重点介绍了 AF 的概念、定义和后生元的益处及其在 AF 解毒中的生物学作用，以及它们在食品制药行业中的益处。