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A Focussed Analysis of Β-cyclodextrins for Quinoxaline Derivatives Synthesis
Current Organic Chemistry ( IF 2.6 ) Pub Date : 2024-03-12 , DOI: 10.2174/0113852728295463240216074814
Hena Khatoon 1 , Emilia Abdul Malek 1, 2
Affiliation  

: Cyclodextrins (CDs), which are a type of cyclic oligosaccharides, are widely used in supramolecular chemistry. For example, they can be used to encapsulate volatile compounds, such as drugs, within their hydrophobic cavity. This encapsulation reduces the volatility of the compounds and helps to retain their desired properties. Due to its extraordinary properties, cyclodextrins have been utilized as catalysts in numerous organic synthesis processes. An intrinsic objective of organic chemists is to optimize the efficacy of organic synthesis through the mitigation of chemical waste and energy expenditure. Utilizing water as a green solvent is, therefore, economical, environmentally sustainable, and secure. It appears that employing water in conjunction with a recyclable catalyst is the most effective method for supramolecular catalysis. As a consequence, we focused this review on the use of water as a solvent and cyclodextrin as a polymer catalyst to produce quinoxaline derivatives in an environmentally friendly and sustainable manner

中文翻译:

用于喹喔啉衍生物合成的β-环糊精的集中分析

:环糊精 (CD) 是一种环状低聚糖,广泛应用于超分子化学。例如,它们可用于将挥发性化合物(例如药物)封装在其疏水腔内。这种封装降低了化合物的挥发性,有助于保留其所需的特性。由于其非凡的性能,环糊精已在许多有机合成过程中用作催化剂。有机化学家的一个内在目标是通过减少化学废物和能源消耗来优化有机合成的功效。因此,利用水作为绿色溶剂是经济的、环境可持续的且安全的。看来,将水与可回收催化剂结合使用是超分子催化最有效的方法。因此,我们的重点是使用水作为溶剂和环糊精作为聚合物催化剂以环境友好和可持续的方式生产喹喔啉衍生物
更新日期:2024-03-12
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