Second-degree burns require greater care, as the damage is more extensive and worrisome and the use of a biomaterial can help in the cell repair process, with better planning, low cost, and better accessibility. Arnica has anti-inflammatory and analgesic properties in skin lesions treatments and laser therapy is another therapeutic alternative for burns. Evaluate the effects of arnica incorporated into PVA associated or not with low intensity laser on burns in rats. PVA and PVA with arnica (PVA+A) were obtained and characterized physicochemically. Through in vivo studies, the effects of PVA and PVA+A with or without the application of laser on the lesions allowed histological and immunohistochemical analyzes. PVA+A was biocompatible and with sustained release of the active, being a promising pharmacological tool and confirmed that laser therapy was effective in accelerating the healing process, due to its potential biomodulator, improving inflammatory aspects, promoting rapid healing in skin lesions.

中文翻译：

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二级烧伤愈合新方法：山金车负载聚乙烯醇膜结合激光治疗

二度烧伤需要更多的护理，因为损伤更广泛、更令人担忧，而生物材料的使用可以帮助细胞修复过程，并且具有更好的规划、低成本和更好的可及性。山金车在皮肤损伤治疗中具有抗炎和镇痛作用，激光疗法是烧伤的另一种治疗选择。评估与低强度激光相关或不相关的 PVA 中掺入山金车对大鼠烧伤的影响。获得 PVA 和 PVA 山金车 (PVA+A) 并进行物理化学表征。通过体内研究，无论是否应用激光，PVA 和 PVA+A 对病变的影响都可以进行组织学和免疫组织化学分析。PVA+A 具有生物相容性并能持续释放活性物质，是一种有前途的药理学工具，并证实激光疗法由于其潜在的生物调节剂而能有效加速愈合过程，改善炎症方面，促进皮肤病变的快速愈合。