Exercise improves quality of life and reduces the side effects of cancer therapies. Nevertheless, attendance to exercise programs remains a challenge for patients. This study explored the feasibility of an exercise program in which women with breast cancer may be allowed to choose among three exercise delivery modalities. Forty-seven patients with breast cancer (stage I-IV) participated in a 12-week combined aerobic and resistance training program. The exercise modality was chosen by patients according to their preferences and needs among three options: the , the or the . Exercise prescription was similar between the three modalities. Whereas the primary endpoint was feasibility, assessed through recruitment rate, attendance, adherence, dropout rate, tolerability, and safety, secondary endpoints included health-related skills and quality of life. Out of 47 recruited patients, 24 chose the home-based program, 19 the personal training program, and four the group-based program. Six dropouts (13%) were registered, and no severe adverse events were recorded. The median program attendance was 98% for personal training programs, 96% for home-based programs, and 100% for group-based programs, whereas compliance resulted in more than 90% in each modality. At postintervention, a significant increase in cardiorespiratory fitness, lower body flexibility, and body weight was observed. Different quality-of-life domains were improved following the intervention, including physical and social functioning, fatigue, and appetite loss. No significant changes in other parameters were detected. An exercise prescription based on a patient-preferred delivery modality showed high feasibility in women with breast cancer.

中文翻译：

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根据患者偏好为乳腺癌患者提供不同方式的新型运动计划的可行性

锻炼可以提高生活质量并减少癌症治疗的副作用。然而，参加锻炼计划对患者来说仍然是一个挑战。这项研究探讨了一项锻炼计划的可行性，允许乳腺癌女性在三种锻炼方式中进行选择。 47 名乳腺癌（I-IV 期）患者参加了为期 12 周的有氧和阻力联合训练计划。患者根据自己的喜好和需要在以下三个选项中选择锻炼方式： 、 或 。三种方式的运动处方相似。主要终点是可行性，通过招募率、出勤率、依从性、辍学率、耐受性和安全性进行评估，次要终点包括健康相关技能和生活质量。在 47 名招募的患者中，24 名选择家庭计划，19 名选择个人训练计划，4 名选择团体计划。登记中有 6 名中途退出者（13%），并且没有记录到严重不良事件。个人培训项目的参加率中位数为 98%，家庭培训项目为 96%，团体培训项目为 100%，而每种形式的合规率均超过 90%。干预后，观察到心肺健康、下半身灵活性和体重显着增加。干预后，不同的生活质量领域得到改善，包括身体和社会功能、疲劳和食欲不振。未检测到其他参数的显着变化。基于患者偏好的分娩方式的运动处方在患有乳腺癌的女性中显示出高度的可行性。