Over the years, polysaccharides such as chitosan, alginate, hyaluronic acid, k-carrageenan, xanthan gum, carboxymethyl cellulose, pectin, and starch, alone or in combination with proteins and/or synthetic polymers, have been used to engineer an extensive portfolio of hydrogels with remarkable features. The application of polysaccharide-based hydrogels has the potential to alleviate challenges related to bioavailability, solubility, stability, and targeted delivery of phytocompounds, contributing to the development of innovative and efficient drug delivery systems and functional food formulations. This review highlights the current knowledge acquired on the preparation, features and applications of polysaccharide/phytocompounds hydrogel-based hybrid systems in wound management, drug delivery, functional foods, and food industry. The structural, functional, and biological requirements of polysaccharides and phytocompounds on the overall performance of such hybrid systems, and their impact on the application domains are also discussed.

中文翻译：

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多糖水凝胶的发展趋势及其在增强植物化合物生物利用度和生物活性方面的作用

多年来，多糖如壳聚糖、藻酸盐、透明质酸、卡拉胶、黄原胶、羧甲基纤维素、果胶和淀粉，单独或与蛋白质和/或合成聚合物组合，已被用于设计广泛的产品组合具有显着特征的水凝胶。多糖水凝胶的应用有可能缓解与植物化合物的生物利用度、溶解度、稳定性和靶向递送相关的挑战，有助于开发创新、高效的药物递送系统和功能性食品配方。本综述重点介绍了目前在伤口处理、药物输送、功能性食品和食品工业中基于多糖/植物化合物水凝胶的混合系统的制备、特性和应用方面获得的知识。还讨论了多糖和植物化合物对此类混合系统整体性能的结构、功能和生物学要求，以及它们对应用领域的影响。